Primordial follicle activation as new treatment for primary ovarian insufficiency
Primordial follicle activation is a process in which individual primordial follicles leave their dormant state and enter a growth phase. While existing hormone stimulation strategies targeted the growing follicles, the remaining dormant primordial follicles were ruled out from clinical use. Recently, in vitro activation (IVA), which...
- Далее -Epigenetic alterations of the first trimester placenta: insight into preoccupying concerns in assisted reproductive technology
Our concerns for the possibility of epigenetic alterations of the developing embryo are recent preoccupations. Yet, the concept of ‘epigenetics' actually dates to 1942. Conrad H. Waddington first coined the term of epigenetics for describing the interactions existing between the genes and their environment (i.e. between the genotype...
- Далее -End of anonymity: stepping into the dawn of communication and a new paradigm in gamete donor counseling
Donor anonymity appears to be going the way of the slide rule and the dodo bird. As early as 2010 professionals in our field began to recognize that the rise of increasingly sophisticated internet technology, facial recognition, and direct to consumer DNA testing would inevitably erode if not eliminate the...
- Далее -A counterintuitive lesson in family planning? Patience first: taking a «gap year» after live birth from assisted reproductive technology before frozen embryo transfer is performed
Many women and couples undergoing assisted reproductive technology (ART) treatment are in a hurry. They are often painfully aware of their «biological clocks,» as many of these patients are in their mid to late thirties and may also desire more than one child. Many may have waited for months, and sometimes...
- Далее -Obstetrical and neonatal outcomes after transfer of cleavage-stage and blastocyst-stage embryos derived from monopronuclear zygotes: a retrospective cohort study
Objective To evaluate the outcomes of embryo transfer with the use of monopronuclear (1PN) zygotes, and the risks of congenital malformations and postpartum developmental disorders. Design Retrospective cohort study. Setting Tertiary-care academic medical center. Patient (s) This study included patients who underwent single embryo...
- Далее -Comparison of the follicular output rate after controlled ovarian stimulation with daily recombinant follicle-stimulating hormone versus corifollitropin alfa
Objective To compare the Follicular Output Rate (FORT) between corifollitropin alfa (CFA) and recombinant follicle-stimulating hormone (rFSH) during controlled ovarian stimulation (COS). Study design This retrospective analysis compared FORT between women treated with CFA or rFSH from three clinical trials: ENGAGE (N = 1476; ages 18−36,...
- Далее -Impact of infertility and infertility treatments on quality of life and levels of anxiety and depression in women undergoing in vitro fertilization
This study aims to evaluate levels of anxiety and depression in women, correlated with infertility per se and with infertility treatments, highlighting predictors of higher levels of distress. Two validated standardized questionnaires, the Hospital Anxiety and Depression Scale (HADS) and the Fertility Quality of Life...
- Далее -The effect of myoinositol on ovarian blood flows in women with polycystic ovary syndrome
5To evaluate whether 4 gram myoinositol and 400 mcg folic acid (MYO) therapy has any effects on ovarian stromal blood flow by using pulsed and color Doppler at 3 months follow-up period in polycystic ovary syndrome (PCOS). One-hundred eighty patients were designed into six groups; Group 1: PCOS patients that received OCP containing...
- Далее -Evaluation of anti-Müller hormone AMH levels in obese women after sleeve gastrectomy
Abstract Introduction: The link between obesity epidemic in fertile age and fertility reduction, in relation with BMI increase, has been demonstrated. An inverse proportionality between BMI and anti-Müller hormone (AMH) has been investigated. This hormone is strictly related to ovarian function. It has been demonstrated that...
- Далее -Effects of controlled ovarian stimulation on thyroid stimulating hormone in infertile women
Abstract Objective：To study the effects of long-acting gonadotropin-releasing hormone agonist (GnRH-a) on thyroid function in euthyroid patients of in vitro fertilization (IVF)/intracytoplasmic sperm injection of embryo transfer (ICSI-ET) and to investigate the timing and alteration of thyroid stimulating hormone...
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